Disclosed is a capacitive pressure sensing circuit and a capacitance-to-voltage converter thereof. The pressure sensing circuit comprises a converter, a cancellation circuit and a signal processor. The cancellation circuit is connected between the converter and at least one capacitive pressure sensor. The cancellation circuit attenuates the inductive capacitance generated by the capacitive pressure sensor to prevent an overflow happening when the inductive capacitance received by the converter is too large, such that the converter can effectively output a voltage signal corresponding to the attenuated inductive capacitance.