Invention Grant
- Patent Title: Compounds and compositions for the inhibition of NAMPT
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Application No.: US16212360Application Date: 2018-12-06
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Publication No.: US10456382B2Publication Date: 2019-10-29
- Inventor: Kenneth W. Bair , Timm R. Baumeister , Alexandre J. Buckmelter , Karl H. Clodfelter , Peter Dragovich , Francis Gosselin , Bingsong Han , Jian Lin , Dominic J. Reynolds , Bruce Roth , Chase C. Smith , Zhongguo Wang , Po-Wai Yuen , Xiaozhang Zheng
- Applicant: Forma TM, LLC , Genentech, Inc.
- Applicant Address: US MA Watertown US CA South San Francisco
- Assignee: FORMA TM, LLC,Genentech, Inc.
- Current Assignee: FORMA TM, LLC,Genentech, Inc.
- Current Assignee Address: US MA Watertown US CA South San Francisco
- Agency: Choate, Hall & Stewart LLP
- Agent Michael A. Shinall; Erica M. D'Amato
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D487/04 ; C07D491/048 ; A61K31/4355 ; A61K31/496 ; A61K31/437 ; C07D491/04 ; C07D495/04 ; A61K31/4365 ; A61K31/497 ; A61K31/519 ; A61K31/5377 ; A61K31/55 ; A61K45/06

Abstract:
The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below:
Public/Granted literature
- US20190105307A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT Public/Granted day:2019-04-11
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