Invention Grant
- Patent Title: Human catestatin induces gut microbiota dysbiosis
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Application No.: US15569045Application Date: 2016-04-25
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Publication No.: US10463712B2Publication Date: 2019-11-05
- Inventor: Jean-Eric Ghia , Mohammed Fazle Alam Rabbi , Ehsan Khafipour , Peris Munyaka
- Applicant: University of Manitoba
- Agency: Ade & Comapny Inc.
- Agent Michael R. Williams; Ryan W. Dupuis
- International Application: PCT/CA2016/050477 WO 20160425
- International Announcement: WO2016/176760 WO 20161110
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K38/16 ; A61K38/00 ; C07K14/00 ; A61K38/17 ; C07K14/575

Abstract:
Treatment with catestatin changes the proportion of two major phyla Bacteroidetes and Firmicutes in the gut microbiota in an opposite manner observed in intestinal disorders like IBD, IBS or non-intestinal disorders like obesity. Specifically, administration of an effective amount of catestatin increased the relative percentage of Bacteroidetes and decreased the relative percentage of Firmicutes in the gut microbiota.
Public/Granted literature
- US20180125927A1 Human Catestatin Induces Gut Microbiota Dysbiosis Public/Granted day:2018-05-10
Information query
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