A method for quantifying intrinsic dimensions of radiation sensors, particularly ionizing radiation sensors, and a device for implementing the method. The method for quantifying the intrinsic dimensions of a radiation sensor includes: defining and modeling the sensor using a schematic diagram of the sensor, determining via numerical computation and via experimental design theory elements that affect the sensor, measuring various specific spatial positions around the sensor, via a multi-frequency calibration source of the radiation, and designing, via experimental design theory, the elements that affect a response of the sensor.