• 专利标题: Formulations of aminoglycoside and fosfomycin in combination for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis
  • 申请号: US14232546
    申请日: 2012-07-12
  • 公开(公告)号: US10471083B2
    公开(公告)日: 2019-11-12
  • 发明人: Alan Bruce Montgomery
  • 申请人: Alan Bruce Montgomery
  • 申请人地址: US TX Austin
  • 专利权人: SAVARA INC.
  • 当前专利权人: SAVARA INC.
  • 当前专利权人地址: US TX Austin
  • 代理机构: VLP Law Group, LLP
  • 代理商 Kurt T. Mulville
  • 国际申请: PCT/US2012/046559 WO 20120712
  • 国际公布: WO2013/010041 WO 20130117
  • 主分类号: A61K31/7036
  • IPC分类号: A61K31/7036 A61K31/665 A61K9/00
Formulations of aminoglycoside and fosfomycin in combination for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis
摘要:
The present invention is antibiotic compositions, ventilator based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an in-line nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
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