Invention Grant
- Patent Title: Method for modulating car-induced immune cells activity
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Application No.: US15517708Application Date: 2015-10-07
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Publication No.: US10472613B2Publication Date: 2019-11-12
- Inventor: Philippe Duchateau , Alexandre Juillerat , Laurent Poirot
- Applicant: CELLECTIS
- Applicant Address: FR Paris
- Assignee: CELLECTIS
- Current Assignee: CELLECTIS
- Current Assignee Address: FR Paris
- Agency: Arrigo, Lee, Guttman & Mouta-Bellum LLP
- Priority: DK201470623 20141007
- International Application: PCT/EP2015/073197 WO 20151007
- International Announcement: WO2016/055551 WO 20160414
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C12N5/16 ; C07K14/725 ; C12N5/078 ; C12N5/0783 ; C12N5/10 ; C12N5/07 ; C12N15/02 ; C12N15/87
Abstract:
The present invention relates to a method to modulate the level of activation of an engineered immune cell (such as a Chimeric Antigen Receptor T-cell) for immunotherapy. The present invention also relates to cells obtained by the present method, preferably comprising said modulable/tunable chimeric antigen receptors for use in therapeutic or prophylactic treatment.
Public/Granted literature
- US20170292118A1 METHOD FOR MODULATING CAR-INDUCED IMMUNE CELLS ACTIVITY Public/Granted day:2017-10-12
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