Provided are an ESD protection diode and an electronic device including the same. An ESD protection diode and an electronic device including the same according to an embodiment of the inventive concept include first to fifth wells. The first well is connected to a first voltage terminal. The second well is connected to a second voltage terminal. The third well is connected to the input/output terminal. The fourth well is disposed between the first well and the third well, and the fifth well is disposed between the second well and the third well. The first to third wells are N-type wells, and the fourth and fifth wells are P-type wells. The first well includes a first N+ diffusion region and the second well includes a second N+ diffusion region. The fourth well includes a first P+ diffusion region and the fifth well includes a second P+ diffusion region. According to an embodiment of the inventive concept, an internal circuit is protected fro an ESD pulse applied to a plurality of terminals and holding voltage is increased.