Microwave interference mitigation techniques and systems are disclosed herein. In some embodiments, microwave interference mitigation involves coordinating wireless traffic in accordance with a magnetron's on-and-off cycle so that data is not sent during the magnetron's on period, and is exclusively sent during the magnetron's off period. Wireless traffic can be coordinated using a voltage monitoring and zero-crossing point detection technique coupled with a Clear To Send (CTS) packet. For non-microwave devices, wireless traffic coordination can be achieved using a pattern matching algorithm coupled with a Clear Channel Assessment (CCA) threshold adjustment during the magnetron's on-and-off cycles. Additional, or alternative, microwave interference mitigation techniques involve decreasing a maximum packet size for data packets that are to be transmitted wirelessly in the environment, which guarantees successful transmission of data packets during the magnetron's off periods.