The present disclosure is directed towards systems and methods for rewriting a HTTP response transmitted via a clientless SSL VPN session. An intermediary device may identify, in a HTTP response transmitted via a clientless SSL VPN session, an absolute URL that includes a first hostname of the server. The device may provide a unique string corresponding to the first hostname of the server. The device may generate a URL segment by combining the unique string with a second hostname of the device. The device may rewrite the absolute URL by replacing the first hostname in the absolute URL with the generated URL segment. A domain name system (DNS) server for the client may be configured with a DNS entry comprising a wildcard combined with the second hostname, to cause the DNS server to resolve the rewritten absolute URL to an IP address of the device.