Embodiments of the present disclosure provide an uplink power control method, a user equipment and a base station. The method comprises: receiving configuration information of a channel state information reference signal CSI-RS from the base station, wherein the configuration information of the CSI-RS comprises reference signal port information and reference signal power information; and measuring a path loss for uplink power control based on the configuration information of the CSI-RS. The embodiments of the present disclosure use the CSI-RS to measure the path loss, which differs from a common CRS in that the CSI-RS may aim at a specific base station. Therefore, path loss measurement may be performed in respect of a target base station of uplink transmission, enabling the path loss compensation to match the actual path loss, thus improving the performance of uplink power control.