A can inspection device includes a rotation device rotating cans, an imaging device taking images of rotating cans, and an image processor processing taken images. The imaging device includes a first camera taking an image of an entire can and a second camera taking an image of an opening-side end portion of the can. The image processor includes an image inspection means for inspecting whether printing is performed properly as compared with a master image by using the image taken by the first camera, a density measurement means for measuring densities in designated positions for respective colors by using the image taken by the first camera, and a printing misalignment value measurement means for measuring misalignment values with respect to set positions of printing misalignment inspection marks printed on the opening-side end portion of the can for respective colors by using the image taken by the second camera.