- 专利标题： Inhibitors of cellular necrosis and related methods
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申请号： US15897787申请日： 2018-02-15
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公开(公告)号： US10508102B2公开(公告)日： 2019-12-17
- 发明人: Junying Yuan , Yijun Zhou , Shan Qian , Dawei Ma
- 申请人： President and Fellows of Harvard College , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 申请人地址： US MA Cambridge CN Shanghai
- 专利权人： President and Fellows of Harvard College,Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 当前专利权人： President and Fellows of Harvard College,Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 当前专利权人地址： US MA Cambridge CN Shanghai
- 代理机构： Choate, Hall & Stewart LLP
- 代理商 Brenda H. Jarrell; Nicholas J. Pace
- 优先权： CN201410764426 20141211; CN201410767595 20141211
- 主分类号： C07D403/06
- IPC分类号： C07D403/06 ; C07D233/78 ; A61P29/00 ; A61P9/10
摘要：
A compound having the following structure (I): or a pharmaceutically acceptable salt, prodrug, stereoisomer or tautomer thereof, is provided. Related compounds, methods for preparation of the same and uses of the compounds for treatment of various indications, including treatment of necrotic cell diseases and/or inflammation, are also provided.
公开/授权文献
- US20190023690A1 INHIBITORS OF CELLULAR NECROSIS AND RELATED METHODS 公开/授权日：2019-01-24
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