Cable ties including an antimicrobial component and optionally a detectable component are disclosed. More particularly, cable ties including a composition having a base plastic, an antimicrobial additive and optionally a detectable additive selected from a detectable metal additive, an X-ray detectable additive and combinations thereof as well as methods of making the same are disclosed. Also, cable ties including an antimicrobial metallic barb and a composition having a base plastic and optionally an antimicrobial additive and/or a detectable additive selected from a detectable metal additive, an X-ray detectable additive and combinations thereof are disclosed.