Invention Grant
- Patent Title: Methods and compositions comprising a combination of a VEGF antagonist and an anti-CTLA-4 antibody
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Application No.: US15959595Application Date: 2018-04-23
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Publication No.: US10532096B2Publication Date: 2020-01-14
- Inventor: Ella Ioffe , Israel Lowy , Gavin Thurston , Elena Burova
- Applicant: REGENERON PHARMACEUTICALS, INC.
- Applicant Address: US NY Tarrytown
- Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee: REGENERON PHARMACEUTICALS, INC.
- Current Assignee Address: US NY Tarrytown
- Agent Lisa Dornbach Flanagan; Frank R. Cottingham; Karl Bozicevic
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K38/17 ; C07K16/28 ; A61K9/00 ; C07K14/71 ; C07K16/22 ; A61K39/00
Abstract:
The present invention provides pharmaceutical compositions comprising a VEGF antagonist and an anti-CTLA-4 antibody, and methods of use thereof. The compositions and methods of the present invention are useful for the treatment of cancers and other diseases and disorders in which anti-angiogenic therapies and/or targeted immune responses may be beneficial.
Public/Granted literature
- US20180236070A1 METHODS AND COMPOSITIONS COMPRISING A COMBINATION OF A VEGF ANTAGONIST AND AN ANTI-CTLA-4 ANTIBODY Public/Granted day:2018-08-23
Information query
