Provided are a printing result inspection apparatus, a method, and a program capable of determining a printing defect caused by a printing step and a printing paper defect caused by printing paper by reading the printing paper once. A printing result inspection apparatus 10 accepts designation of paper defect information used for determining a defected region through an operation unit 14. A defect determination unit 24 determines whether defected regions D10, D12, and D14 extracted from a non-image region A10 are the printing defect or the printing paper defect based on designated paper defect information, a density change amount, and a color, and an image feature amount of a defected region determined as the printing paper defect in the non-image region A10 is stored in paper defect information I10 and is accumulated in a paper defect information storage unit 30. The defect determination unit 24 performs the determination of defected regions D20 and D22 extracted from image regions A20 and A22 based on the designated paper defect information, stored paper defect information relating to printing paper P10 being inspected, and the paper defect information I10.