Invention Grant
- Patent Title: Antibodies against TIM3 and uses thereof
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Application No.: US16017489Application Date: 2018-06-25
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Publication No.: US10533052B2Publication Date: 2020-01-14
- Inventor: Xiao Min Schebye , Mark J. Selby , Michelle Minhua Han , Christine Bee , Andy X. Deng , Anan Chuntharapai , Brigitte Devaux , Huiming Li , Paul O. Sheppard , Alan J. Korman , Daniel F. Ardourel , Ekaterina Deyanova , Richard Huang , Guodong Chen , Michelle Kuhne , Hong-An Truong
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: Sterne, Kessler, Goldstein & Fox, P.L.L.C.
- Main IPC: C07K16/30
- IPC: C07K16/30 ; C07K16/28 ; A61K47/68 ; A61P35/00 ; G01N33/574 ; A61K39/00

Abstract:
Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.
Public/Granted literature
- US20180298097A1 ANTIBODIES AGAINST TIM3 AND USES THEREOF Public/Granted day:2018-10-18
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