A method and system for obtaining images of an object of interest using a system comprising an X-ray source facing a detector. The method and system enable the acquiring of a plurality of 2D projection images of the object of interest in a plurality of orientations. A selected 2D projection image such as the zero projection of the plurality of projections can be enhanced by using at least a subset of the plurality of tomosynthesis projection images. The obtained enhanced 2D projection image is displayed for review.