- 专利标题: T cell immunotherapy specific for WT-1
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申请号: US14813782申请日: 2015-07-30
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公开(公告)号: US10538572B2公开(公告)日: 2020-01-21
- 发明人: Thomas M. Schmitt , Philip D. Greenberg , Hieu Nguyen
- 申请人: Fred Hutchinson Cancer Research Center
- 申请人地址: US WA Seattle
- 专利权人: FRED HUTCHINSON CANCER RESEARCH CENTER
- 当前专利权人: FRED HUTCHINSON CANCER RESEARCH CENTER
- 当前专利权人地址: US WA Seattle
- 代理机构: Seed IP Law Group LLP
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K39/00 ; C07K14/00 ; C07K16/30 ; C07K14/725 ; A61K35/17 ; A61K38/17 ; A61K38/20 ; A61K38/00
摘要:
The present disclosure provides high affinity and enhanced affinity T cell receptors specific for human Wilms tumor protein 1 (WT-1) epitopes for use in treating diseases or disorders, such as cancer cells that overexpress WT-1.
公开/授权文献
- US20160083449A1 T CELL IMMUNOTHERAPY SPECIFIC FOR WT-1 公开/授权日:2016-03-24
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