Invention Grant
- Patent Title: DNA vaccine containing VEGF-specific epitope and/or angiopoietin-2-specific epitope
-
Application No.: US14424937Application Date: 2013-08-28
-
Publication No.: US10543261B2Publication Date: 2020-01-28
- Inventor: Hironori Nakagami , Mariko Kyutoku , Ryuichi Morishita , Hideki Tomioka
- Applicant: OSAKA UNIVERSITY , ANGES, INC.
- Applicant Address: JP Suita JP Ibaraki
- Assignee: Osaka University,AnGes, Inc.
- Current Assignee: Osaka University,AnGes, Inc.
- Current Assignee Address: JP Suita JP Ibaraki
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: JP2012-191717 20120831
- International Application: PCT/JP2013/073045 WO 20130828
- International Announcement: WO2014/034735 WO 20140306
- Main IPC: C12N7/00
- IPC: C12N7/00 ; C12N15/86 ; A61K39/00
Abstract:
The present invention provides a therapeutic or prophylactic agent for cancer, containing an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of VEGF and/or a specific epitope of angiopoietin-2, wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
Public/Granted literature
- US20150202271A1 DNA VACCINE CONTAINING VEGF-SPECIFIC EPITOPE AND/OR ANGIOPOIETIN-2-SPECIFIC EPITOPE Public/Granted day:2015-07-23
Information query
