- 专利标题: RNAi inhibition of alpha-ENaC expression
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申请号: US15874396申请日: 2018-01-18
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公开(公告)号: US10544418B2公开(公告)日: 2020-01-28
- 发明人: Gino Van Heeke , Emma Hickman , Henry Luke Danahay , Pamela Tan , Anke Geick , Hans-Peter Vornlocher
- 申请人: Arrowhead Pharmaceuticals, Inc.
- 申请人地址: US CA Pasadena
- 专利权人: Arrowhead Pharmaceuticals, Inc.
- 当前专利权人: Arrowhead Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Pasadena
- 代理商 Robert M. Teigen; Paul VanderVelde
- 优先权: EP07110376 20070615; EP07114265 20070813
- 主分类号: C12N15/113
- IPC分类号: C12N15/113 ; A61K31/713 ; A61K45/06
摘要:
The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.
公开/授权文献
- US20180148726A1 RNAi Inhibition of Alpha-ENaC Expression 公开/授权日:2018-05-31
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