A toothbrush (100) having a combination of tapered and non-tapered cleaning elements (50) for enhanced cleaning effects and having a plurality of tapered bristle tufts of differing tuft configurations including, a first tapered bristle tuft (500) having a dome-shaped bristle tip profile (520) toward one end (210) of the head (200), a second tapered bristle tuft (602) having an arcuate-shaped bristle configuration (622) toward an opposite end (222) of the head (200), and a plurality of laterally-extending third tapered bristle tufts (600) arranged in an alternating fashion with non-tapered bristle tufts (630) and disposed between the first and second tapered bristle tufts (500, 602).