A method, a circuit and a display device for driving an organic light emitting diode, wherein a driving transistor (DTFT) for driving a display element is turned off by jumping one or more of a reference voltage input (Vref), a reset voltage input (Vinit) and a data signal input (Vdata) before beginning to output an EL high level (ELVDD) of a pixel compensation circuit and after beginning to output an EL low level (ELVSS), to overcome the splash screen phenomenon during power-up and direct current-direct current driving failure.