Invention Grant
- Patent Title: Phosphate replacement mRNA cap analogs
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Application No.: US16008662Application Date: 2018-06-14
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Publication No.: US10563195B2Publication Date: 2020-02-18
- Inventor: Gabor Butora , Matthew Stanton , Thomas Steele
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Cooley LLP
- Agent Heidi A. Erlacher; Christine C. Pemberton
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C12N15/10 ; C07H21/02 ; C07D473/18 ; C07D473/34

Abstract:
The present disclosure relates to cap analogs, which can result in high levels of capping efficiency and transcription and improved translation efficiencies. The present disclosure also relates to methods useful for preparing cap analogs and using mRNA species containing such analogs, as well as kits containing the cap analogs.
Public/Granted literature
- US20180305393A1 PHOSPHATE REPLACEMENT MRNA CAP ANALOGS Public/Granted day:2018-10-25
Information query
IPC分类: