Systems and method for operating a gas compressor are disclosed herein. A compressor can have one or more dry gas seals surrounding the central axle of the compressor. The dry gas seals can each be pressurized with a barrier gas or other fluid supply providing a barrier within the dry gas seal. The method can include controlling delivery of a first barrier gas to the one or more dry seals during a startup or initiation of the compressor. The method can include controlling delivery of a second barrier gas different from the first barrier gas to the one or more dry seals based on the information received from sensors disposed within the compressor that can measure, inter alia, dry seal temperature and pressure within the system. The method can further include terminating the delivery of the first barrier gas based on the sensor information.