Invention Grant
- Patent Title: Substituted urea depsipeptide analogs as activators of the CLPP endopeptidase
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Application No.: US16329168Application Date: 2017-09-01
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Publication No.: US10570179B2Publication Date: 2020-02-25
- Inventor: Richard E. Lee , Ying Zhao
- Applicant: St. Jude Children's Research Hospital
- Applicant Address: US TN Memphis
- Assignee: St. Jude Children's Research Hospital
- Current Assignee: St. Jude Children's Research Hospital
- Current Assignee Address: US TN Memphis
- Agency: Ballard Spahr LLP
- International Application: PCT/US2017/049902 WO 20170901
- International Announcement: WO2018/045313 WO 20180308
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K11/02 ; A61K45/06 ; A61P31/04 ; A61K38/15
Abstract:
In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Public/Granted literature
- US20190185517A1 SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE Public/Granted day:2019-06-20
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