The present application discloses a touch substrate including a base substrate, and a touch electrode layer on the base substrate having a first region having a plurality of first mesh electrode patterns, a second region having a plurality of second mesh electrode patterns corresponding to the plurality of first mesh electrode patterns, and an interface region between the first region and the second region. Each of the plurality of first mesh electrode patterns includes a plurality of first mesh electrode lines having a first line width. A corresponding second mesh electrode pattern includes a plurality of second mesh electrode lines corresponding to the plurality of first mesh electrode lines and having the first line width. The first mesh electrode line in the interface region has a second line width no less than the first line width.