The present invention relates to novel subtilase polypeptides exhibiting increased wash performance and/or improved wash performance and to compositions comprising such polypeptides. The polypeptides of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the polypeptides, expression vectors, host cells, and methods for producing and using the polypeptides of the invention.