The present disclosure relates to the field of display technology and provides an addressing method of a spatial light modulator, a holographic display device and a control method thereof, which can simplify the addressing process of the spatial light modulator. The addressing method of the spatial light modulator comprises the steps of: dividing the spatial light modulator to obtain one or more modulation regions, each modulation region comprising M loading subregions, and each loading subregion comprising at least one pixel unit, wherein M≥2, and M is a positive integer; and addressing one loading subregion of each modulation region within a frame so as to load holographic data of a frame of a hologram to all the pixel units of all the addressed loading subregions.