Invention Grant
- Patent Title: Triazole DAGLα inhibitors
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Application No.: US15778207Application Date: 2016-12-02
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Publication No.: US10583137B2Publication Date: 2020-03-10
- Inventor: Benjamin F. Cravatt , Daisuke Ogasawara , Andreu Viader , Hui Deng , Tom Van Der Wel , Marcelis Van Der Stelt
- Applicant: THE SCRIPPS RESEARCH INSTITUTE , LEIDEN UNIVERSITY
- Applicant Address: US CA La Jolla NL Leiden
- Assignee: THE SCRIPPS RESEARCH INSTITUTE,LEIDEN UNIVERSITY
- Current Assignee: THE SCRIPPS RESEARCH INSTITUTE,LEIDEN UNIVERSITY
- Current Assignee Address: US CA La Jolla NL Leiden
- Agency: Wilson Sonsini Goodrich & Rosati
- International Application: PCT/US2016/064844 WO 20161202
- International Announcement: WO2017/096315 WO 20170608
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/454 ; A61K31/4439 ; A61K31/4192 ; A61K31/506 ; A61P25/28

Abstract:
Provided herein are triazole compounds and pharmaceutical compositions comprising said compounds useful as modulators of DAGL(α) and DAGL(β). In some embodiments, the compounds described herein are selective DAGL(α) inhibitors. Furthermore, the subject compounds and compositions are useful for the treatment of neurodegenerative or neuroinflammatory disease.
Public/Granted literature
- US20180344729A1 TRIAZOLE DAGLAlpha INHIBITORS Public/Granted day:2018-12-06
Information query
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