A lamination manufacturing method for large-sized metal components with complicated structures is provided, relating to a part manufacturing method to solve the problem that traditional machining, entire plastic forming and the existing additive manufacturing method are difficult to manufacture large-sized metal components with complicated special-shape structure and high-performance requirement. The manufacturing method includes the steps: step 1. obtaining a three-dimensional digital model of a large-sized metal component with complicated structure, and dividing the model into a plurality of slice layers; step 2. selecting the actually available metal sheet corresponding to the thickness of each slice layer divided in step 1, and machining each metal sheet to obtain a shaped sheet consistent with the model of each slice layer in step 1; step 3. stacking the shaped sheets obtained through machining of step 2 according to the order of the corresponding slice layers in step 1; and step 4. obtaining a required large-sized metal component with complicated structure after all the shaped sheets are connected into a whole. The present invention is used for shaping large-sized components with complicated deep cavity and inner hole structures.