Methods and apparatus to implement aging compensation for emissive displays with subpixel rendering are disclosed. An example apparatus includes a converter to convert red-green-blue (RGB) data to subpixel rendering (SPR) data. The RGB data is indicative of an image to be rendered on an emissive display screen. The apparatus includes a compensator to apply pixel correction values to the SPR data to generate corrected SPR data to compensate for pixel degradation. The apparatus further includes a usage accumulator to track pixel usage based on the corrected SPR data. The apparatus also includes a correction calculator to calculate the pixel correction values based on the pixel usage.