- 专利标题: Ophthalmic drug sustained release formulation and uses thereof
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申请号: US15722227申请日: 2017-10-02
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公开(公告)号: US10603274B2公开(公告)日: 2020-03-31
- 发明人: Deepank Utkhede , Catherine Jones , David Wiseman
- 申请人: MATI THERAPEUTICS INC.
- 申请人地址: US TX Austin
- 专利权人: Mati Therapeutics Inc.
- 当前专利权人: Mati Therapeutics Inc.
- 当前专利权人地址: US TX Austin
- 代理商 Koren Anderson
- 主分类号: A61F9/00
- IPC分类号: A61F9/00 ; A61K31/165 ; A61K31/569 ; A61K38/13 ; A61K47/10 ; A61K9/00 ; A61K47/34 ; A61K9/14 ; A61F9/007 ; A61K31/573
摘要:
A solid matrix sustained release ophthalmic formulation for topical delivery of a solid ophthalmic drug to the eye, medical devices, drug cores, drug inserts and drug delivery systems comprising the formulation, methods of manufacturing the formulation, medical devices and their methods thereof for delivering the ophthalmic drug for a treatment period provided herein. The formulation disclosed herein is an admixture of an ophthalmic drug, and a combination of a hydrophobic polymer, a hydrophilic polymer and a surfactant, wherein the drug is eluted daily over an extended period of time at therapeutic dose of drug.
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