Invention Grant
- Patent Title: 2-amino-6-(difluoromethyl)-5,5-difluoro-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors
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Application No.: US16059715Application Date: 2018-08-09
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Publication No.: US10603310B2Publication Date: 2020-03-31
- Inventor: Karsten Juhl , Lena Tagmose , Mauro Marigo
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DK2014000648 20141110; DK2015000447 20150807
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; C07D401/12 ; A61K31/444 ; C07D417/12 ; C07D413/12 ; A61K31/497 ; A61P25/28
Abstract:
The present invention is directed to compounds of formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of Aβ deposits is beneficial such as Alzheimer's disease.
Public/Granted literature
- US20190000823A1 2-AMINO-6-(DIFLUOROMETHYL)-5,5-DIFLUORO-6-PHENYL-3,4,5,6-TETRAHYDROPYRIDINES AS BACE1 INHIBITORS Public/Granted day:2019-01-03
Information query
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