- 专利标题： Targeting NAD+ to treat chemotherapy and radiotherapy induced cognitive impairment, neuropathies and inactivity
-
申请号： US15570210申请日： 2016-04-28
-
公开(公告)号： US10603334B2公开(公告)日： 2020-03-31
- 发明人: Lindsay Edward Wu , David A. Sinclair
- 申请人： NewSouth Innovations Pty Ltd
- 申请人地址： AU Sydney
- 专利权人： NewSouth Innovation Pty. Limited
- 当前专利权人： NewSouth Innovation Pty. Limited
- 当前专利权人地址： AU Sydney
- 代理机构： Foley Hoag LLP
- 代理商 David P. Halstead
- 国际申请： PCT/US2016/029765 WO 20160428
- 国际公布： WO2016/176437 WO 20161103
- 主分类号： A61K31/706
- IPC分类号： A61K31/706 ; A61K31/455 ; A61K31/443 ; A61K31/7076 ; A61K31/52 ; A61P25/02 ; A61K38/45
摘要：
Methods and compositions for preventing or treating peripheral neuropathy, cognitive deficits, inactivity, depression, chemotherapy and/or radiotherapy induced peripheral neuropathy and cognitive deficits, and improving cognitive performance, in a subject in need thereof are disclosed. The disclosed methods include the step of administering to the subject an effective amount of an agent that increases the level of NAD+ in the subject.
公开/授权文献
信息查询
