Invention Grant
- Patent Title: Substituted 5-cyanoindole compounds and uses thereof
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Application No.: US16012468Application Date: 2018-06-19
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Publication No.: US10604502B2Publication Date: 2020-03-31
- Inventor: Lei Du-Cuny , Qitao Xiao , Guoliang Xun , Qiangang Zheng
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Daniel E. Raymond
- Priority: WOPCT/CN2017/089020 20170719
- Main IPC: C07D401/04
- IPC: C07D401/04 ; A61P35/00 ; A61P35/02 ; C07D209/14 ; C07D409/14 ; C07D401/14 ; C07D405/14 ; C07D471/04 ; C07D498/04 ; A61K31/4439 ; A61K31/404 ; A61K31/4709 ; A61K31/437 ; A61K31/4375 ; A61K31/5383 ; C07D403/04

Abstract:
A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for the treatment of lysine (K)-specific demethylase 1A (LSD1)-mediated diseases or disorders: wherein R1, R2, R3, R4, and R5 are as defined herein.
Public/Granted literature
- US20190023684A1 SUBSTITUTED 5-CYANOINDOLE COMPOUNDS AND USES THEREOF Public/Granted day:2019-01-24
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