- 专利标题： Heteroaryl substituted pyridines and methods of use
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申请号： US16165662申请日： 2018-10-19
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公开(公告)号： US10604515B2公开(公告)日： 2020-03-31
- 发明人: Robert J. Altenbach , Andrew Bogdan , Ghjuvanni Petru Diunisu Coti , Marlon D. Cowart , Stephen N. Greszler , Hans Kelgtermans , Philip R. Kym , Steven Emiel Van der Plas , Xueqing Wang
- 申请人： AbbVie S.à.r.l. , Galapagos NV
- 申请人地址： LU Luxembourg BE Mechelen
- 专利权人： AbbVie S.á.r.l.,Galapagos NV
- 当前专利权人： AbbVie S.á.r.l.,Galapagos NV
- 当前专利权人地址： LU Luxembourg BE Mechelen
- 代理机构： Quarles & Brady LLP
- 主分类号： C07D413/04
- IPC分类号： C07D413/04 ; C07D413/14 ; C07D417/04 ; C07D417/14 ; A61K31/4439 ; A61K31/444 ; A61K45/06
摘要：
The invention discloses compounds of Formula I, wherein X1, X2, R1, and R2 are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
公开/授权文献
- US20190055229A1 Heteroaryl Substituted Pyridines and Methods of Use 公开/授权日：2019-02-21
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