- Patent Title: High purity RNA compositions and methods for preparation thereof
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Application No.: US16001786Application Date: 2018-06-06
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Publication No.: US10653712B2Publication Date: 2020-05-19
- Inventor: Stephen Hoge , William Issa , Edward J. Miracco , Jennifer Nelson , Amy E. Rabideau , Gabor Butora
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12P19/34
- IPC: C12P19/34 ; A61K31/7105 ; C07K14/505 ; A61P33/00 ; A61P31/12 ; A61P31/04 ; A61P35/00 ; C12N15/10 ; G01N33/68
Abstract:
The invention relates to improved RNA compositions for use in therapeutic applications. The RNA compositions are particularly suited for use in human therapeutic application (e.g., in RNA therapeutics). The RNA compositions are made by improved processes, in particular, improved in vitro-transcription (IVT) processes. The invention also relates to methods for producing and purifying RNA (e.g, therapeutic RNAs), as well as methods for using the RNA compositions and therapeutic applications thereof.
Public/Granted literature
- US20180363019A1 HIGH PURITY RNA COMPOSITIONS AND METHODS FOR PREPARATION THEREOF Public/Granted day:2018-12-20
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