Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a renal nerve modulation device. The renal nerve modulation device may include an elongate shaft. A balloon may be coupled to the shaft. The balloon may have a hydrophilic electrode region. A sensor may be coupled to the balloon and may be disposed adjacent to the hydrophilic electrode region. An electrode may be coupled to the catheter shaft and may be disposed within the balloon.