Intermediates in the synthesis of eribulin and related methods of synthesis

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US10676481B2 Intermediates in the synthesis of eribulin and related methods of synthesis 有权

Patent Title: Intermediates in the synthesis of eribulin and related methods of synthesis
Application No.: US16076028

Application Date: 2017-02-10
Publication No.: US10676481B2

Publication Date: 2020-06-09
Inventor: Phil S. Baran , Charles E. Chase , Francis G. Fang
Applicant: EISAI R&D MANAGEMENT CO., LTD.
Applicant Address: JP Tokyo
Assignee: EISAI R&D MANAGEMENT CO., LTD.
Current Assignee: EISAI R&D MANAGEMENT CO., LTD.
Current Assignee Address: JP Tokyo
Agency: Clark & Elbing LLP
International Application: PCT/US2017/017501 WO 20170210
International Announcement: WO2017/139664 WO 20170817
Main IPC: C07D493/00
IPC: C07D493/00 ; C07D493/22

Abstract:

The invention relates to methods and intermediates useful in the synthesis of eribulin.

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