The present disclosure discloses a pixel structure, including a reflective layer, a reflective electrode, a flexible electrode and a bottom electrode sequentially disposed along a direction of incident light. An optical resonant cavity is formed between the reflective layer and the reflective electrode, the reflective layer and the flexible electrode are connected to each other; and a first voltage is loaded between the reflective electrode and the flexible electrode, and a second voltage is loaded between the flexible electrode and the bottom electrode; depending on at least one of changes of the first voltage and the second voltage, the flexible electrode deforms along the direction of incident light, and drives the reflective layer to move along the direction of incident light. The present disclosure also discloses a display substrate and a control method thereof and a display device.