Systems and methods for detecting improper presentation of content items by applications executing on client devices. A method can include receiving a content package including a first content item, a second content item and an interaction confirmation script, the interaction confirmation script configured to execute within an application and cause the application to detect, responsive to the first content item presented, a first interaction event with the first content item; present, upon detecting the first interaction event on the first content item, the second content item; detect a second interaction event with the second content item; transmit, upon detecting the second interaction event, a confirmation of the first interaction event; and transmit a request to access an information resource linked to the second content item. The method can further include presenting the information resource responsive to the second interaction event on the second content item.