Invention Grant
- Patent Title: KRas G12C inhibitors
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Application No.: US16191190Application Date: 2018-11-14
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Publication No.: US10689377B2Publication Date: 2020-06-23
- Inventor: James F. Blake , Laurence E. Burgess , Mark Joseph Chicarelli , James Gail Christensen , Adam Cook , Jay Bradford Fell , John P. Fischer , Matthew Arnold Marx , Macedonio J. Mejia , Pavel Savechenkov , Guy P. A. Vigers , Christopher Ronald Smith , Martha E. Rodriguez
- Applicant: Mirati Therapeutics, Inc. , Array BioPharma Inc.
- Applicant Address: US CA San Diego US CO Boulder
- Assignee: Mirati Therapeutics, Inc.,Array Biopharma Inc.
- Current Assignee: Mirati Therapeutics, Inc.,Array Biopharma Inc.
- Current Assignee Address: US CA San Diego US CO Boulder
- Agency: Wood, Phillips, Katz, Clark & Mortimer
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P35/00 ; C07D491/08
Abstract:
The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
Public/Granted literature
- US20190144444A1 KRAS G12C INHIBITORS Public/Granted day:2019-05-16
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