Invention Grant
- Patent Title: Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine
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Application No.: US16408701Application Date: 2019-05-10
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Publication No.: US10702486B2Publication Date: 2020-07-07
- Inventor: Thomas Jerussi , Qun Kevin Fang , Mark G. Currie
- Applicant: SUNOVION PHARMACEUTICALS INC.
- Applicant Address: US MA Marlborough
- Assignee: SUNOVION PHARMACEUTICALS INC.
- Current Assignee: SUNOVION PHARMACEUTICALS INC.
- Current Assignee Address: US MA Marlborough
- Agency: Heslin Rothenberg Farley & Mesiti, P.C.
- Main IPC: A61K31/135
- IPC: A61K31/135 ; C07C211/42

Abstract:
Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful.
Public/Granted literature
- US20200000746A1 TREATMENT OF CNS DISORDERS WITH trans 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE Public/Granted day:2020-01-02
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