Invention Grant
- Patent Title: Mutant 3-hydroxybutyrate dehydrogenase from Rhodobacter sphaeroides as well as methods and uses involving the same
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Application No.: US16059096Application Date: 2018-08-09
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Publication No.: US10704029B2Publication Date: 2020-07-07
- Inventor: Daniela Beck , Mara Boenitz-Dulat , Peter Kratzsch , Thomas Streidl , Carina Horn
- Applicant: Roche Diagnostics Operations, Inc. , Roche Diabetes Care, Inc.
- Applicant Address: US IN Indianapolis
- Assignee: Roche Diabetes Care, Inc.
- Current Assignee: Roche Diabetes Care, Inc.
- Current Assignee Address: US IN Indianapolis
- Agency: Dinsmore & Shohl LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@a39a5cf
- Main IPC: C12N9/02
- IPC: C12N9/02 ; C12N9/04 ; C12Q1/32 ; C12P7/18
Abstract:
The present invention relates to a mutant 3-hydroxybutyrate dehydrogenase (3-HBDH) with improved performance relative to the wild-type 3-HBDH, a nucleic acid encoding the mutant 3-HBDH, a cell comprising the mutant 3-HBDH or the nucleic acid, a method of determining the amount or concentration of 3-hydroxybutyrate in a sample, and a device for determining the amount or concentration of 3-hydroxybutyrate in a sample.
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