A universal cover for hygiene cloth dispensers includes a flexible pouch for holding hygiene cloths stored in a plurality of different hygiene cloth dispensers. The flexible pouch has a top wall, a bottom wall, and an interior space between the top and bottom walls. The universal cover includes a seam that can be opened to an open position and resealed to a closed position to connect the top wall to the bottom wall. The open position defines a refill opening for receiving the different hygiene cloth dispensers. A dispensing opening is formed in the top wall of the universal cover. The dispensing opening is reinforced against deformation due to exposure to moisture, body oils, dirt, and stretching. The dispensing opening is sized such that different sized movable and non-movable covers of at least two different commercial hygiene cloth dispensers are accessible through the dispensing opening.