An arrangement of operating multi-task interactive electronic devices includes at least one processor, a screen module and two or more input modules. The processor executes at least a first application and a second related application with different interactive programs at the same time. The screen module is operatively linked to the processor. The screen module comprises at least a display screen having two or more display areas two or more applications thereon respectively. Two or more input modules are operatively linked to the processor, wherein the applications are able to be simultaneously controlled and operated by the input modules respectively.