Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating an adapter for sending Applicability Statement 4 (AS4) profile compliant payloads. In one aspect, a method includes receiving a configuration script including parameters for an adapter for sending Applicability Statement 4 (AS4) profile compliant payloads to an agency; identifying a conformance client and at least one associated Processing Mode (P-Mode) based on the configuration script; identifying a response handler based on the configuration script, wherein the response handler is configured to receive and parse responses from the agency; generating the adapter to include the conformance client and the response handler, wherein the conformance client is associated with an authentication service, the authentication service determined based on the configuration script, and wherein the at least one P-Mode are populated based on the configuration script; and enabling the generated adapter for execution in a runtime environment.