An electrically operated aerosol-generating system is provided, including an aerosol-generating device, and first and second removable aerosol-forming cartridges each including a resistive heater. The first cartridge includes a first aerosol-forming substrate having a first heating profile and the second cartridge includes a second aerosol-forming substrate having a second heating profile. The device includes a main body defining a cavity and at least one opening configured to removably receive one of the first and second cartridges in the cavity; an electrical power supply and a controller configured to control a supply of electrical current from the power supply to the heater, to detect whether the first or second cartridge has been received within the cavity based upon a resistive load of the respective heater, and to control the supply of electrical current to the heater according to either the first or the second heating profile in response to a detected cartridge.