A liquid crystal composition, a liquid crystal display (LCD) device using the liquid crystal composition, and a method of manufacturing an LCD device are provided. The liquid crystal display device comprises: a first substrate; a liquid crystal layer disposed on the first substrate, the liquid crystal layer including a liquid crystal compound; and a first liquid crystal alignment layer disposed between the first substrate and the liquid crystal layer, wherein the first compound includes a first compound, which has at least one hydrophilic group bonded to one end of a core structure thereof and a benzoyl derivative moiety bonded to the other end of the core structure thereof.