Embodiments described herein provide a method for accessing a host memory through non-volatile memory over fabric bridging with direct target access. A first memory access command encapsulated in a first network packet is received at a memory interface unit and from a remote direct memory access (RDMA) interface and via a network fabric. The first memory access command is compliant with a first non-volatile memory interface protocol and the first network packet is compliant with a second non-volatile memory interface protocol. The first network packet is unwrapped to obtain the first memory access command. The first memory access command is stored in a work queue using address bits of the work queue as a pre-set index of the first memory access command. The first memory access command is sent from the work queue based on the pre-set index to activate a first target storage device.